Treatment

What is Re2O?

Re2O is a skin booster, which is an injectable treatment placed into the upper layers of the skin rather than used to add volume. Re:berry describes it as a rejuvenation booster that helps replenish skin components that decline with age, sun exposure and stress. The goal is better skin quality: more hydration, a smoother surface and a fresher look, rather than a change in facial shape.

Skin boosters are popular in Korea because they work on the condition of the skin itself. Many patients describe their goal as skin that looks well rested and holds moisture better, which matches Re:berry's philosophy of stable improvement over short-lived change. The doctor will explain the specific formulation used and why it suits your skin at consultation.

How does Re2O differ from other boosters?

Re:berry offers several boosters, and each is chosen for a different job. Very broadly:

Rejuran Healer uses polynucleotides and is often chosen for skin repair, texture and fine lines
Laetigen is discussed in the context of collagen support and firmness
CellREDM is often considered for skin regeneration and scar-prone skin
Re2O is focused on replenishing components for hydration and overall rejuvenation

If you are unsure which booster is right for you, our comparison of Laetigen vs Re2O explains how the doctor decides. In many cases, the choice depends on whether dryness, texture, laxity or scarring is the main concern.

Who is Re2O good for?

Re2O may suit adults who notice:

Skin that feels tight or dry even with a good moisturizer
Dullness, fine crepey texture or makeup that does not sit smoothly
A tired look after travel, long flights or seasonal changes in Seoul
A wish to maintain skin quality alongside lifting treatments such as Ultherapy or Thermage

It is less likely to be the right first choice for deep folds, significant volume loss or sagging. Those concerns usually need fillers, energy-based lifting or a combination plan.

Why dehydration matters in Seoul

Seoul has dry, cold winters with heated indoor air, and humid summers with long hours in air-conditioned spaces. Both can leave skin feeling tight or looking flat. Many residents of Mapo-gu and visitors arriving on long-haul flights describe their skin as dehydrated rather than truly dry, meaning it lacks water more than oil. A booster such as Re2O is one way to support the skin from within, while a good barrier routine, humidifier use and daily sunscreen remain the foundation at home.

What happens during a Re2O session?

Consultation and skin check

The doctor assesses your skin type, hydration, sensitivity and any active acne or irritation. You will be asked about allergies, blood-thinning medications, recent procedures and pregnancy or breastfeeding. A written plan is agreed before treatment.

Numbing

Numbing cream is usually applied for around 20 to 40 minutes to make the injections more comfortable.

Injection

The booster is delivered in many tiny injections, by hand or with an injection device, depending on the technique the doctor chooses. This typically takes 10 to 20 minutes for the full face. Most people describe the sensation as a series of quick pricks with mild pressure.

Immediately after

Small raised bumps at the injection points are common and usually flatten within a day or so. A soothing mask or cooling may be applied before you leave.

How many sessions do I need?

Many patients start with two or three sessions spaced two to four weeks apart, then move to maintenance every few months. Some notice a hydrated look within the first week, but the more meaningful change in skin quality usually develops over two to four weeks and builds with each session. For a broader view, see how often you should get skin boosters. Results vary by individual.

Side effects and who should avoid Re2O

Common, usually temporary effects include:

Redness, small bumps or mild swelling for one to three days
Tiny bruises at some injection points, which may take up to a week to fade
Tenderness when touching the skin

Less common risks include infection, allergic reaction or uneven texture. Treatment is usually postponed if you have active infection, cold sores or inflamed acne in the area. Tell the doctor if you are pregnant, breastfeeding, have an autoimmune condition or take blood thinners or supplements that increase bruising.

Aftercare tips

Avoid makeup for the rest of the day unless advised otherwise
Skip saunas, jjimjilbang, intense exercise and alcohol for about 24 hours
Use gentle cleansing and a simple moisturizer for a few days
Use sunscreen daily and avoid exfoliating acids and retinoids until the skin settles

More detail is in our aftercare guide for skin boosters.

Pricing and booking at Re:berry Hongdae

Pricing depends on the area treated, the number of sessions and whether Re2O is combined with other treatments. Your plan and cost are confirmed in writing at consultation. See Location & Hours for the address and opening hours, or request an appointment via our Booking page.

Is Re2O the same as a filler?

No. Fillers are placed deeper to add volume or reshape areas such as the cheeks or lips. Re2O is a skin booster placed in the upper skin layers to improve hydration and texture, so it should not change your facial shape. Some patients use both, with each treatment planned for a different purpose by the doctor.

Can I wear makeup after Re2O?

Most clinics suggest waiting until the next day so that the tiny injection points can close and the risk of irritation or infection stays low. Light, clean mineral makeup is usually acceptable after 24 hours if the skin is calm. Your doctor will give specific advice based on how your skin responds.

Can I fly after a Re2O session?

Many travelers fly a day or two after a skin booster without problems, though cabin air can feel drying and bumps may look more noticeable at first. Keep the skin moisturized, drink water and avoid touching the face. If you have a tight schedule, mention your flight date at consultation so the timing can be planned.

Does Re2O hurt?

With numbing cream, most people find Re2O tolerable, describing quick pricks and pressure rather than strong pain. Areas near the nose and mouth can feel more sensitive. You can ask the practitioner to pause at any time, and the technique can be adjusted to your comfort.