Treatment

What is Rejuran Healer?

Rejuran Healer is an injectable skin booster developed in South Korea. Its main ingredient is polynucleotide (PN), a chain of DNA fragments purified from salmon. PN-based products were first used in regenerative medicine before being adapted for aesthetic skin treatments, and Rejuran has become one of the most requested boosters in Korean clinics.

Unlike filler, Rejuran is not designed to add visible volume or change facial shape. It is a quality-of-skin treatment: the aim is skin that looks healthier, more even and more resilient over time.

How does Rejuran Healer work?

PN is thought to act as a scaffold and signal in the skin's repair environment. Research and manufacturer data suggest it may support fibroblast activity, which is linked to collagen production, and help the skin's natural recovery processes. The evidence base is growing but is still smaller than for older treatments, so expectations should be realistic.

In practice, many patients notice improvements in:

Skin texture and smoothness
A more hydrated, less dull appearance
Fine crepey lines, especially around the eyes and cheeks
Skin resilience after irritation or repeated laser sessions

Rejuran Healer vs other Rejuran products

The Rejuran family includes several variants. Rejuran Healer is the general full-face booster. Rejuran i (often called Rejuran Eye) uses a formulation intended for the thin skin around the eyes, and Rejuran S is used for depressed scars. Your doctor will suggest which, if any, fits your skin. For the eye area specifically, see Rejuran Healer for Under-Eye Hollows and Dark Circles.

Who is Rejuran Healer suitable for?

Rejuran is often considered by people who want gradual, natural-looking improvement rather than structural change. It may suit you if you have:

Thin, dry or sensitized skin that looks tired
Fine lines and enlarged-looking pores linked to poor skin quality
Mild post-acne texture
Skin recovering from frequent laser or peel treatments

Who should avoid it?

Because the product is derived from salmon, people with fish or salmon allergy should tell the doctor and will usually be advised against it. Rejuran is typically avoided during pregnancy and breastfeeding, over active infection or inflamed acne in the treatment zone, and in people with uncontrolled bleeding disorders. Mention any blood-thinning medication or supplements at consultation.

What happens during treatment?

Skin assessment: A doctor reviews your skin type, concerns and any recent treatments.
Numbing: Topical anesthetic cream is applied, usually for 30 to 40 minutes.
Injection: Small amounts of PN are placed across the face using a fine needle in a grid pattern, or with an injector device in some protocols.
Soothing: A calming mask or cooling may follow.

The injection itself typically takes 15 to 20 minutes for a full face. If you are wondering about comfort, read Does Rejuran hurt?

What does recovery look like?

Expect small raised bumps at injection points; these usually flatten within 1 to 3 days. Mild redness, tenderness and occasional pinpoint bruising are also common. Most people can return to work the next day, though the bumps are visible on the day of treatment.

Avoid makeup for about 24 hours unless your doctor says otherwise.
Skip saunas, hot baths and intense workouts for 1 to 2 days.
Do not rub or massage the bumps.
Use gentle cleanser, moisturizer and sunscreen.

Our page on Aftercare After Skin Boosters covers this in more detail.

How many sessions do I need, and how long does it last?

A common starting plan is three sessions spaced 2 to 4 weeks apart, followed by maintenance every 4 to 6 months for many patients. Effects build gradually, and some people notice change after the first session while others need the full course. Results vary by individual and depend on age, skin condition and lifestyle.

Can Rejuran be combined with other treatments?

Yes. Re:berry's approach is to design a combination of treatments rather than rely on a single procedure. Rejuran is frequently paired with laser toning, pico lasers or energy-based lifting, and the order and spacing are planned by the doctor. Some patients compare it with other boosters such as CellREDM, PDRN or exosomes; see Rejuran vs PDRN vs Exosome.

Is Rejuran right for a first-time patient?

For many first-timers, Rejuran is an approachable starting point because it does not change facial shape and the side effects are usually short-lived. That said, it is still an injection treatment with a needle in the skin dozens of times, so comfort and expectations should be discussed openly. If you mainly want a quick glow before an event, a HydraFacial or a light laser may fit the schedule better, with Rejuran planned as a longer-term course afterward.

It also helps to keep skincare simple during the course: avoid starting new strong actives such as retinoids or exfoliating acids in the few days around each session unless your doctor approves.

Booking Rejuran at Re:berry Hongdae

Pricing depends on the product variant, the area and the number of sessions, and is confirmed in writing at consultation. Multilingual consultation support is available; confirm languages when booking. See Location & Hours for the branch address and request a time through our Booking page.

Is Rejuran Healer the same as PDRN?

They are related but not identical. Both are derived from salmon DNA. PDRN uses shorter DNA fragments, while PN in Rejuran consists of longer chains that form a gel-like structure in the skin. Clinics use them for overlapping goals, and the choice depends on skin type and the doctor's plan.

When will I see results from Rejuran?

Skin may look more hydrated within one to two weeks once the bumps settle, but texture and elasticity changes are usually gradual. Many patients judge results after the second or third session, about one to two months after starting. Results vary by individual.

Can I do Rejuran during a short trip to Seoul?

A single session fits a short trip, but bumps are visible for a day or so, so avoid scheduling it right before photos or events. If you plan a full course, your doctor can advise on spacing or continuing at another Re:berry branch.