Treatment

What are exosomes?

Exosomes are extremely small vesicles, or bubbles, released by cells. They carry proteins, lipids and genetic signaling material from one cell to another, acting a little like messengers. In skin care and aesthetic medicine, exosome-based formulas are used with the aim of supporting the skin's own repair and renewal signals.

The exosomes used in aesthetic products are usually derived from cultured cells or plant sources and are processed into a concentrated solution. Research in this area is still developing, so it is reasonable to see exosome therapy as a supportive treatment that complements other procedures rather than a standalone fix.

How is exosome therapy delivered?

Because exosome solutions need to reach beneath the surface to be most useful, they are typically applied immediately after a treatment that opens microchannels in the skin. Common pairings at Re:berry include:

Microneedling: fine needles create tiny channels, and the solution is applied during or right after.
Laser treatments: applied after lasers such as Genesis laser or toning to help the skin settle.
Ultrasound infusion: devices such as LDM may be used to help with absorption and soothing.
Booster plans: combined with injectable boosters as part of a skin-quality program.

The delivery method affects comfort, downtime and how often sessions are scheduled, so the doctor chooses it based on your skin and goals.

What can exosome therapy help with?

Exosome therapy is commonly considered for:

Recovery after laser or resurfacing: helping redness and sensitivity settle.
Dull, tired-looking skin: as part of a plan to improve radiance and texture.
Acne scars: as a supporting step alongside microneedling or lasers.
Sensitive or reactive skin: when combined with gentle, calming protocols.
Enlarged pores and rough texture: often combined with other treatments.

It is not designed for lifting sagging skin, adding volume or removing deep pigment such as stubborn melasma on its own.

Who should avoid or delay exosome therapy?

Exosome treatments are generally well tolerated, but the doctor will check for situations where it should be postponed:

pregnancy or breastfeeding;
active skin infection, cold sores or open wounds;
a current flare of eczema or severe rosacea, unless a calming protocol is planned;
a history of cancer or immune conditions, which should be discussed with your own physician;
recent isotretinoin use if microneedling is planned.

What to expect at Re:berry Hongdae

Consultation: the doctor examines your skin and decides whether exosomes add value to your plan.
Cleansing and preparation: makeup is removed and numbing may be applied if microneedling is used.
Primary treatment: microneedling, laser or another procedure is performed.
Exosome application: the solution is applied or infused, sometimes followed by a soothing mask.
Aftercare briefing: you receive written instructions before leaving.

Downtime and side effects

Exosome application itself is usually gentle. Most downtime comes from the paired procedure. After microneedling, redness can last one to three days, with mild dryness or flaking afterwards. After light lasers, redness often settles within hours.

Possible side effects include temporary redness, tightness, mild swelling and, rarely, irritation or an allergic-type reaction. Keep skincare simple for a few days, avoid exfoliating acids and retinoids, and use sunscreen every day. See our laser aftercare guide for detail.

How many sessions are needed?

Many plans involve three to five sessions spaced two to four weeks apart, with maintenance as needed. Changes are gradual and build across sessions rather than appearing after one visit. Results vary by individual.

Exosomes vs other regenerative boosters

Exosomes, PDRN and polynucleotide boosters such as Rejuran are often grouped together, but they differ in form and delivery. Exosomes are typically applied topically after a channel-opening treatment, while PDRN and Rejuran are usually injected. Read Rejuran vs PDRN vs Exosome for a direct comparison.

How should I prepare for exosome therapy?

A little preparation helps the skin respond well and reduces irritation, particularly if microneedling is part of the session:

stop retinoids, exfoliating acids and scrubs about three to five days beforehand;
avoid sunburn or deliberate tanning in the two weeks before treatment;
tell the doctor about any medications, supplements and recent procedures;
arrive with clean skin or allow time for makeup removal at the clinic;
plan a quiet evening afterward rather than a sauna or a late night out.

If you have a history of cold sores, mention it, as the doctor may suggest precautions before microneedling.

Why does Re:berry treat exosomes as part of a plan?

Re:berry's approach is to diagnose first and then design a combination of treatments, rather than selling one procedure in isolation. Exosomes fit this philosophy because they are most useful when they support another step, such as helping skin recover after a laser for pigmentation or calming the skin during an acne scar program. Building the plan around your diagnosis aims for stable, gradual improvement rather than a short-lived glow.

Pricing and booking

Pricing depends on the delivery method, the area and the number of sessions, and it is confirmed in writing at consultation. For the address and hours, see Location & Hours, and request an appointment on the Booking page.

Are exosomes the same as stem cells?

No. Exosomes are tiny vesicles released by cells, not cells themselves. Aesthetic exosome products contain these vesicles in a processed solution and do not contain living cells. They are used to support signaling involved in skin recovery. The doctor can explain the source of the specific product used at Re:berry Hongdae during consultation.

Is there downtime after exosome therapy?

The exosome application is usually gentle, so downtime mainly depends on what it is paired with. After microneedling, expect redness for one to three days and some dryness. After light lasers, redness often fades within hours. Many people return to sightseeing the same or next day with sunscreen.

Can exosome therapy help acne scars?

Exosome therapy is generally used as a supporting step in acne scar plans, often after microneedling or lasers, to help the skin recover and remodel. It is rarely enough on its own for deeper scars. The doctor will recommend a combination based on your scar types, and results vary by individual.

How soon can I repeat exosome therapy?

Sessions are commonly spaced two to four weeks apart so the skin can recover between treatments, especially when microneedling is involved. The interval depends on the paired procedure and how your skin responds. Your treatment plan at Re:berry Hongdae will set out a schedule after the first session.