Rejuran Healer is a polynucleotide skin booster that may soften fine lines by supporting skin repair, hydration and elasticity. At Re:berry Hongdae it is commonly used for crepey under-eyes, cheek texture and early lines that are not caused mainly by muscle movement. Most patients have three sessions about four weeks apart, with gradual improvement over several weeks.
Re:berry Clinic Hongdae · Information reviewed for accuracy · Results vary by individual.
Why Rejuran Healer for fine lines?
Fine lines come in two main types. Dynamic lines appear when muscles move, such as crow's feet when you smile. Static lines are visible even at rest and often reflect thinning, dry or less elastic skin. Rejuran Healer is suited mostly to the second type.
Its polynucleotide fragments are thought to support the skin's natural repair processes, improve hydration and help the dermal environment. Rather than filling a line, it aims to improve the quality of the skin around it, so lines look softer and the surface looks smoother.
Who is it suitable for?
- Fine, crepey lines under the eyes and on the cheeks
- Skin that looks thin, dry or tired despite good skincare
- People who want a natural-looking improvement without added volume
- Those who prefer to avoid or delay toxin for static lines
- Skin recovering from sun damage, harsh treatments or stress
When another treatment may be better
Lines that deepen with expression usually respond more to Botox for wrinkles. Deep folds such as nasolabial lines may need filler or lifting. Many people have both types, which is why combinations are common.
What happens during treatment?
- Consultation: The doctor maps the lines, checks skin thickness and decides on areas and technique.
- Numbing: Topical numbing cream is applied, typically for 20–40 minutes.
- Injection: Small amounts are placed with a fine needle or injector across the treatment area. This usually takes 15–30 minutes.
- Finish: Small raised bumps appear at injection points and a soothing product is applied.
Rejuran injections are often described as more uncomfortable than some other boosters because of the product's thickness. Numbing helps, and you can ask for breaks.
How many sessions are needed?
A common starting course is three sessions about four weeks apart, sometimes up to four for thinner or more sun-damaged skin. Many patients then return every six to twelve months for maintenance. Fine lines improve gradually, and the full effect is usually judged a few weeks after the final session. Results vary by individual.
Downtime and side effects
- Small bumps at injection points, usually settling within one to two days
- Redness and mild swelling, especially under the eyes
- Occasional bruising that may last up to a week
- Rarely, infection or allergic reaction; tell your doctor about fish or salmon allergies
If you are visiting Seoul for a short time, plan Rejuran early in your trip so bumps can settle before photos or events.
Which areas are commonly treated for fine lines?
- Under-eyes: Crepey, thin skin where fine lines and a tired look are common.
- Cheeks: Fine criss-cross lines and rough texture, often from sun exposure.
- Forehead: Static lines that remain after muscle activity is relaxed.
- Neck: Fine horizontal lines and crepey skin that skincare alone rarely improves.
Treating a whole zone, rather than single lines, tends to give a more even, natural improvement in skin quality.
How does Seoul's climate affect fine lines?
Dryness makes fine lines look deeper. In Seoul, cold winters and indoor heating can dehydrate the skin for months, while summer UV accelerates collagen breakdown. Many patients in Hongdae schedule a booster course in autumn to prepare skin for winter, then focus on sun protection through spring and summer. Good daily hydration and sunscreen help any booster result last longer.
Good combinations
- With Botox: Toxin relaxes dynamic lines while Rejuran improves skin quality.
- With energy devices: Thermage FLX or ultrasound lifting support firmness at deeper levels.
- With other boosters: Some plans alternate Rejuran with hydrating boosters, depending on skin needs.
Alternatives
PDRN boosters share similar ingredients in a thinner, often more comfortable form. CellREDM and Laetigen work differently and may suit people focused on collagen or dermal support. Our Rejuran Healer vs CellREDM comparison explains the differences.
Aftercare
Avoid makeup on injection points for the rest of the day, skip saunas, intense exercise and alcohol for 24 hours, and use gentle skincare and sunscreen. Do not massage bumps.
Pricing and booking
Pricing depends on the area, product amount and number of sessions, and is confirmed in writing at consultation. Book through our Booking page.
Key facts
- Ingredient: Polynucleotides (PN) derived from salmon DNA
- Best for: Static fine lines, crepey texture, thin skin
- Sessions: Typically 3, about 4 weeks apart
- Downtime: Small bumps for 1–2 days; possible bruising
- Results seen: Gradually over 2–8 weeks
- Lasts: Commonly 6–12 months with maintenance
Frequently asked questions
Can Rejuran Healer replace Botox for fine lines?
Not exactly. Botox relaxes the muscles that create expression lines, while Rejuran Healer improves skin quality around static lines. For lines visible at rest that are linked to thin or dry skin, Rejuran may be enough. For lines that deepen when you move, Botox is usually more effective, and many people use both.
Is Rejuran Healer good for under-eye fine lines?
The under-eye area is one of the most common places Rejuran is used, because the skin there is thin and prone to crepiness. Some clinics use a version formulated for the eye area. Swelling and bruising may be more noticeable there, so allow a few days before important events.
When will I see results for fine lines?
Some people notice smoother, more hydrated skin within a week or two, once bumps have settled. Changes to fine lines tend to build gradually over two to eight weeks and across a course of sessions. Results vary by individual and depend on skin condition and lifestyle.
Keep reading
Before you book
This page is general information, not a diagnosis. Suitability, dose, number of sessions and expected results are decided by a doctor at consultation, and results vary by individual. Possible side effects include redness, swelling and bruising. Pricing is confirmed in writing before any treatment. See our medical disclaimer.
Start with a diagnosis, not a package
Re:berry Clinic Hongdae designs your plan after a one-to-one skin assessment. Multilingual consultation support is available.