Rejuran does hurt for most people, but usually in a manageable way. Because Rejuran Healer is injected in many tiny points across the face, patients often describe repeated stinging or pinching, even after numbing cream. At Re:berry Hongdae, numbing, cooling and careful technique are used to reduce discomfort, and sensitivity varies by individual and area.
Re:berry Clinic Hongdae · Information reviewed for accuracy · Results vary by individual.
Why does Rejuran feel uncomfortable?
Rejuran Healer contains polynucleotides (PN), a gel that is somewhat thicker than many other boosters. It is placed in small amounts at many points across the skin, so you feel a series of needle pricks and a pressure or sting as the product goes in. The sensation is short at each point, but it repeats many times. Read the full overview at Rejuran Healer.
How do clinics reduce the pain?
- Topical numbing cream: Applied for about 30 to 40 minutes to dull surface sensation.
- Fine needles: Very thin needles reduce the prick.
- Cooling: Cold packs or cooled air before and after injecting areas.
- Pacing: Short pauses when an area feels sensitive.
- Technique choices: Some protocols use an injector device or cannula, depending on area and doctor judgment.
Which areas hurt most?
Thinner, nerve-rich areas such as the sides of the nose, upper lip, forehead and the under-eye region are usually more sensitive than the cheeks. Pain tolerance also changes with sleep, stress and, for some people, the menstrual cycle. If you have had another booster before, Rejuran may feel a little more intense than lighter hyaluronic acid boosters.
What does it feel like afterward?
After treatment, the skin may feel tender, warm and slightly swollen, with small raised bumps at injection sites that typically settle within 1 to 3 days. Pinpoint bruises are possible. Most people return to normal activities the next day. For aftercare guidance, see Aftercare After Skin Boosters.
Tips to make it easier
- Arrive early so numbing has enough time to work.
- Avoid caffeine and alcohol beforehand if they make you more sensitive.
- Tell the doctor if you are nervous; pacing and breaks help.
- Ask whether a smaller area is reasonable for your first session.
Pain is personal, and results vary by individual. If discomfort is your main worry, ask at consultation about alternatives, or read What is numbing cream and how long does it take?
At a glance
- Typical feeling: Repeated stinging or pinching
- Numbing: Topical cream for about 30 to 40 minutes beforehand
- Most sensitive areas: Around the nose, upper lip and under the eyes
- Injection time: About 15 to 20 minutes for a full face
- Afterward: Tenderness and small bumps for 1 to 3 days
Related questions
Is Rejuran more painful than other skin boosters?
Many patients find Rejuran slightly more uncomfortable than lighter hyaluronic acid boosters because the PN gel is thicker. Comfort varies by product, technique and individual sensitivity. Your doctor can explain how the options compare for you. Ask whether a smaller test area or longer numbing time would help with your first session.
Can I take a painkiller before Rejuran?
Some pain relievers, such as aspirin and many anti-inflammatories, can increase bruising. Ask the clinic before taking anything. Acetaminophen is often considered a lower-bruising option, but follow medical advice for your situation. Never stop prescribed blood thinners on your own; check with the doctor who prescribed them first.
Does Rejuran under the eyes hurt more?
The under-eye skin is thin and sensitive, so many people feel it more, though less product is used there. Bruising is also more likely in this area. Numbing and careful technique help. Avoid booking eye-area sessions right before photos or events, and use a gentle cool compress afterward if advised.
Keep reading
Before you book
This page is general information, not a diagnosis. Suitability, dose, number of sessions and expected results are decided by a doctor at consultation, and results vary by individual. Possible side effects include redness, swelling and bruising. Pricing is confirmed in writing before any treatment. See our medical disclaimer.
Still have a question?
A doctor at Re:berry Clinic Hongdae can answer it for your skin specifically. Multilingual consultation support is available.