Rejuran Healer is made mainly of polynucleotides (PN), purified DNA fragments derived from salmon, suspended in a sterile solution for injection. Developed in Korea, it is used as a skin booster to support skin repair, texture and elasticity. At Re:berry Hongdae it is typically given as a series of sessions. Results vary by individual.
Re:berry Clinic Hongdae · Information reviewed for accuracy · Results vary by individual.
What are polynucleotides?
Polynucleotides are chains of nucleotides, the building blocks of DNA. In Rejuran Healer, they are extracted from salmon and purified to remove proteins and other components. When injected into the skin, polynucleotides are thought to support the skin's natural repair processes and create a favorable environment for healthy tissue, which is why Rejuran is often described as a healing booster.
How is this different from other boosters?
- PN vs PDRN: PDRN (polydeoxyribonucleotide) is also derived from salmon DNA but consists of shorter fragments. PN products such as Rejuran use longer chains. See the difference between Rejuran and PDRN.
- PN vs hyaluronic acid: Hyaluronic acid boosters focus mainly on hydration, while PN focuses more on repair and skin quality.
- PN vs exosomes: Exosome treatments use cell-derived vesicles and work through different signaling.
What is Rejuran Healer used for?
Rejuran Healer is commonly used for fine lines, uneven texture, enlarged pores, thin under-eye skin and post-acne skin. Results usually build gradually over a course.
How is Rejuran injected?
After numbing cream for about 20 to 40 minutes, the product is injected in many small, shallow points across the treatment area, either by hand or with an injection device. Small raised bumps form at each point and typically flatten within one to three days. Some patients notice a smoother, more even texture after a few weeks, with improvement building over a series of sessions. Results vary by individual.
Is it safe?
Rejuran is widely used in Korean clinics. Common effects include redness, small bumps and occasional bruising for a few days. Because it is derived from fish, tell the doctor if you have a fish or salmon allergy. Treatment is usually postponed during pregnancy and with active infection. To discuss whether it suits you, book a consultation via our Booking page.
At a glance
- Main ingredient: Polynucleotides (PN)
- Source: Purified salmon DNA
- Origin: Developed in Korea
- Sessions: Often 3, spaced 2–4 weeks apart
- Downtime: Small bumps for about 1–3 days
- Good to know: Mention fish allergies at consultation
Related questions
Is Rejuran Healer vegan?
No. Rejuran Healer is derived from salmon DNA, so it is not suitable for people who avoid animal-derived products. If this matters to you, ask the doctor about alternative boosters that do not use animal sources. Options vary by clinic and goals.
Can I get Rejuran if I am allergic to fish?
Tell the doctor about any fish or seafood allergy before treatment. Although the polynucleotides are highly purified, the doctor may advise against Rejuran or suggest a different booster depending on your allergy history. Bring any allergy records you have, and mention past reactions to injections or skincare.
Does Rejuran contain hyaluronic acid?
The original Rejuran Healer is based on polynucleotides rather than hyaluronic acid. Some related products in the wider Rejuran range combine PN with other ingredients. The doctor will explain exactly which product is used in your plan. You can ask to see the product packaging.
Keep reading
Before you book
This page is general information, not a diagnosis. Suitability, dose, number of sessions and expected results are decided by a doctor at consultation, and results vary by individual. Possible side effects include redness, swelling and bruising. Pricing is confirmed in writing before any treatment. See our medical disclaimer.
Still have a question?
A doctor at Re:berry Clinic Hongdae can answer it for your skin specifically. Multilingual consultation support is available.