The most common side effects of skin boosters are small raised bumps at injection points, redness, mild swelling, tenderness and pinpoint bruising, which usually settle within 1–7 days. Rarer risks include infection, allergic reaction and persistent lumps. At Re:berry Hongdae, a doctor reviews your history before treatment to reduce these risks. Results vary by individual.
Re:berry Clinic Hongdae · Information reviewed for accuracy · Results vary by individual.
What side effects are common?
Skin boosters such as Rejuran Healer, PDRN, Laetigen, CellREDM and Re2O are injected in many small points across the skin. Typical effects include:
- Bumps: small raised spots where product was placed, usually flattening in 1–3 days
- Redness and swelling: often settle within hours to a day
- Bruising: pinpoint bruises that may last up to a week
- Tenderness: mild soreness when touching the area
Thicker products, such as polynucleotide boosters, may cause more visible bumps than lighter ones.
What rarer risks should I know about?
- Infection at injection sites
- Allergic reactions, for example to fish-derived or collagen-based ingredients
- Lumps or nodules that last longer than expected
- Pigment changes, particularly in skin prone to hyperpigmentation
Who should avoid or postpone boosters?
- People who are pregnant or breastfeeding
- Those with active skin infection, cold sores or open wounds in the area
- Anyone with an allergy to an ingredient, such as fish for PDRN or polynucleotides
- Those with flaring autoimmune skin conditions, unless cleared by a doctor
How can I reduce side effects?
Avoid alcohol and blood-thinning supplements beforehand if your physician agrees, skip makeup until the next day, avoid saunas and intense exercise for 24–48 hours, and do not massage the bumps. See aftercare after skin boosters and reducing bruising after injections. Contact the clinic promptly if pain, heat or redness increases.
How do side effects compare between boosters?
Side effects are broadly similar across boosters, but there are differences worth knowing. Thicker polynucleotide products may cause bumps that are more visible for a day or two. Lighter products such as PDRN often spread more easily. Collagen-based boosters require attention to collagen allergies. Treatments delivered with an injector device may leave a grid of small marks, while hand injections may leave slightly larger individual bumps. The doctor will explain what to expect for the specific product and technique in your plan, so you can schedule around work, events or flights.
At a glance
- Common: Bumps, redness, swelling, tenderness
- Typical duration: 1–3 days; bruises up to about a week
- Rare: Infection, allergy, persistent nodules
- Avoid if: Pregnancy, active infection, relevant allergies
- Contact clinic if: Increasing pain, heat, spreading redness
Related questions
How long do bumps last after a skin booster?
Most bumps flatten within one to three days. Thicker boosters may leave visible bumps a little longer. If a bump stays firm for more than a couple of weeks or becomes painful, contact the clinic for a review. Avoid massaging bumps, which can irritate the skin.
Can skin boosters cause breakouts?
Some people notice small breakouts after injections, sometimes from makeup applied too early or skin irritation. Keeping skin clean, avoiding makeup until the next day and using gentle products usually helps. Tell the clinic if breakouts are significant. Changing your pillowcase that night can also help.
Are skin boosters safe for sensitive skin?
Many people with sensitive skin receive boosters, and some products are chosen specifically for calming and repair. The doctor will check your history and may suggest a patch approach, gentler technique or a different product. Mention any recent reactions or flare-ups at your consultation.
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Before you book
This page is general information, not a diagnosis. Suitability, dose, number of sessions and expected results are decided by a doctor at consultation, and results vary by individual. Possible side effects include redness, swelling and bruising. Pricing is confirmed in writing before any treatment. See our medical disclaimer.
Still have a question?
A doctor at Re:berry Clinic Hongdae can answer it for your skin specifically. Multilingual consultation support is available.